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Publicaciones (últimos años)

“Molecular and cellular mechanisms involved in the Trypanosoma cruzi/host cell interplay”, Romano PS, Cueto JA, Casassa AF, Vanrell MC, Gottlieb RA, Colombo MI. IUBMB Life. 2012 May; 64(5) 387-396.

“Polyamine depletion inhibits the autophagic response modulating Trypanosoma cruzi infectivity” Vanrell MC, Cueto JA, Barclay JJ, Carrillo C, Colombo MI, Gottlieb RA, and Romano PS. Autophagy 2013: 9(7)1-14.

“Sequence variation in CYP51A from the Y strain of Trypanosoma cruzi alters its sensitivity to inhibition” Cherkesova TS, Hargrove TY, Vanrell MC, Ges I, Usanov SA, Romano PS, Lepesheva GI. FEBS Lett. 2014 Nov 3;588(21):3878-85.

“Computer-guided drug repurposing: Identification of trypanocidal activity of clofazimine, benidipine and saquinavir” Bellera CL, Balcazar DE, Vanrell MC, Casassa AF, Palestro PH, Gavernet L, Labriola CA, Gálvez J, Bruno-Blanch LE, Romano PS, Carrillo C, Talevi A. Eur J Med Chem. 2015; 93C:338-348.

“High-throughput drug repositioning for the discovery of new antichagasic medications” Bellera C, Sbaraglini M, Balcazar D, Fraccaroli L, Vanrell MC, Casassa AF, Labriola CA, Romano PS, Carrillo C, Talevi  A. Mini Rev Med Chem. 2015;15(3):182-93.

“Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option” Sbaraglini ML, Vanrell MC, Bellera CL, Benaim G, Carrillo C, Talevi A, Romano PS. Curr Top Med Chem. 2016 16(19):2201-22. Review.

“Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)”. Klionsky, D. J. et al, Autophagy. 2016 Jan 2; 12(1):1-222.

“Drugs for the etiologic treatment of Chagas disease: Myths and Truths” Rivero CV and Romano PS. Inter. Cardiovac. Forum Research. (Review in the Special Issue: Chagas Disease). (

“SNARE proteins required during Trypanosoma cruzi parasitophorous vacuole development” Cueto JA, Vanrell, MC, Salassa BN, Nola S, Galli T, Colombo MI and Romano PS. Cell Microbiol 2017 Jun; 19(6).

“The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists”. Balcazar DE, Vanrell MC, Romano PS, Pereira CA, Goldbaum FA, Bonomi HR, Carrillo C. PLoS Negl Trop Dis. 2017 Apr 13;11(4).

“The regulation of autophagy differentially affects Trypanosoma cruzi metacyclogenesis.” Vanrell MC, Losinno AD, Cueto JA, Balcazar D, Carrillo C and Romano PS. PLoS Negl Trop Dis. 2017 Nov 1;11(11).

“Chronic Infections: A Possible Scenario for Autophagy and Senescence Cross-Talk” Aguilera MO, Delgui LR, Romano PS and Colombo MI.  Cells 2018, 7, 162.

“Autophagy: A necessary process during the Trypanosoma cruzi life-cycle” Salassa BN and Romano PS. Virulence 2018, Nov 29; 1-10.

“Trypanosoma cruzi invasion in non-phagocytic cells: an ultrastructural study” Cueto JA, Santos E, de Souza, W and Romano PS. Biocell 2018, 42 (3).

“Trypanosoma rangeli: growth in mammalian cells in vitro and action of a repositioned drug (17-AAG) and a natural extract (Artemisia essential oil)”. Cimador AL*, Galante EL*, Muñoz LI*, Romano PS, Losinno AD, Vanrell MC, Biocell 2018.