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Publicaciones (últimos 5 años)

– The host Rab9a/Rab32 axis is actively recruited to the Trypanosoma cruzi parasitophorous vacuole and benefits the infection cycle, Salassa BN, Cueto JA, Vanrell, MC, Descoteaux A and Romano PS. (Molecular Microbiology, MMI-2023-19297, en prensa).

– Autophagy as an innate immunity response against pathogens: a Tango dance. Aguilera, MO; Delgui, LR; Reggiori, F; Romano, PS and Colombo MI. Febs Letters, FEBS Lett. 2023 Dec 15. doi: 10.1002/1873-3468.14788. Online ahead of print.

– Autophagy in protists and their hosts: when, how and why? Romano PS, Akematsu T, Besteiro S, Bindschedler A, Carruthers VB, Chahine Z, Coppens I, Descoteaux A, Alberto Duque TL, He CY, Heussler V, Le Roch KG, Li FJ, de Menezes JPB, Menna-Barreto RFS, Mottram JC, Schmuckli-Maurer J, Turk B, Tavares Veras PS, Salassa BN, Vanrell MC. Autophagy Rep. 2023; 2(1):2149211. doi: 10.1080/27694127.2022.2149211. Epub 2023 Mar 9.

– Induction of Autophagy by Ursolic Acid Promotes the Elimination of Trypanosoma cruzi Amastigotes From Macrophages and Cardiac Cells. Vanrell MC, Martínez SJ, Muñoz LI, Salassa BN, Gambarte Tudela J, Romano PS. . Front Cell Infect Microbiol. 2022 Jul 8;12:919096. doi: 10.3389/fcimb.2022.919096. eCollection 2022.

– Biological features of TcM: A new [Trypanosoma cruzi] isolate from Argentina classified into TcV lineage. Martinez SJ, Nardella JN, Rodríguez ME, Rivero CV, Agüero F and Romano PS*. Curr. Res. Microb.. Sci. 2022 Jun 30;3:100152. doi: 10.1016/j.crmicr.2022.100152. eCollection 2022.

– Biogenesis and Breakdown of Lipid Droplets in Pathological Conditions. Fader Kaiser CM,* Romano PS*, Vanrell MC, Pocognoni CA, Jacob J, Caruso B, Delgui LR. Front Cell Dev Biol. 2022 Feb 7;9:826248. doi: 10.3389/fcell.2021.826248. eCollection 2021.

– Repurposing Carvedilol as a Novel Inhibitor of the [Trypanosoma cruzi] Autophagy Flux That Affects Parasite Replication and Survival. Rivero CV, Martínez SJ, Novlck P, Cueto JA, Salassa BN, Vanrell MC, Li X, Labriola, CA, Polo LM, Engman DM, Clos J, Romano PS. Front Cell Infect Microbiol. 2021 Aug 12;11:657257. doi: 10.3389/fcimb.2021.657257. eCollection 2021.

– Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Klionsky D et al, Autophagy 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280.

– Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of [Trypanosoma cruzi] infection. Li X, Yi S, Scariot DB, Martinez SJ, Falk BA, Olson CL, Romano PS, Scott EA, Engman DM. JCI Insight 2021 10;6(9):145523. doi: 10.1172/jci.insight.145523.

– Induction of autophagy increases the proteolytic activity of reservosomes during Trypanosoma cruzi metaciclogénesis. Losinno AD, Martínez SJ, Labriola CA, Carrillo C, Romano PS. Autophagy 2021 17(2) 439-456. DOI: 10.1080/15548627.2020.1720428.

– Endocytic Rabs are recruited to the Trypanosoma cruzi parasitophorous vacuole and contribute to the process of infection. Salassa BN, Cueto JA, Gambarte Tudela J and Romano PS. Front Cell Infect Microbiol. 2020 10:210. doi: 10.3389/fcimb.2020.00210. eCollection 2020.

– Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy. Santiago J. Martinez, Patricia S. Romano*, David M. Engman* (*corresponding authors). Review. Front. Cell Inf. Microbiol. 2020 May 8; 10:210.

– Autophagy plays a protective role against [Trypanosoma cruzi] infection in mice. Casassa AF, Vanrell MC, Colombo MI, Gottlieb RA, Romano PS. Virulence 2019 Dec;10(1):151-165. doi: 10.1080/21505594.2019.1584027.

– Mitochondrial stress triggers a pro-survival response through epigenetic modifications of nuclear DNA. Mayorga L, Salassa BN, Marzese DM, Loos MA, Eiroa HD, Lubieniecki F, García Samartino C, Romano PS, Roqué M. Cell Mol Life Sci. 2019 Jan 23. doi: 10.1007/s00018-019-03008-5.

Trypanosoma rangeli: growth in mammalian cells in vitro and action of a repositioned drug (17-AAG) and a natural extract (Artemisia essential oil). Cimador AL*, Galante EL*, Muñoz LI*, Romano PS, Lossino AD, Vanrell MC. Biocell 2019, 43(1): 13-19.