Publicaciones
1) Buzzatto MV, Berberián MV, Di Bartolo AL, Masone D and Tomes CN. α-synuclein is required for sperm exocytosis at a post-fusion stage. Frontiers in Cell and Developmental Biology, section Molecular and Cellular Reproduction. Vol 11.doi: 10.3389/fcell.2023.1125988
2) Flores Montero K, Berberián MV, Mayorga LS, Tomes CN and Ruete MC (2023). The molecular chaperone Cysteine String Protein is required to stabilize trans-SNARE complexes during human sperm acrosomal exocytosis. Biology of Reproduction 108, 229-2403)
3) Di Bartolo A; Tomes CN; Mayorga L; Masone D (2022). Journal of Chemical Theory and Computation 18, 4544-4554
4) Caparotta M, Tomes CN, Mayorga L, Masone D (2020). The Synaptotagmin-1 C2B domain is a key regulator in the stabilization of the fusion pore. Journal of Chemical Theory and Computation 16, 7840-7851.
5) Moreno-Irusta A, Dominguez E, Marin-Briggiler C, Matamoros-Volante A, Chiarante N, Yaneff A, Lucchesi O, Tomes CN, Treviño C, Lascano R, Losinno L, Giojalas L (2020). Reactive oxygen species are involved in the signaling of equine sperm chemotaxis. Reproduction 159, 423–436
6) Ruete MC, Zarelli VEP, Masone D, de Paola M, Bustos DM and Tomes CN (2019). A connection between reversible tyrosine phosphorylation and SNARE complex-disassembly activity of NSF unveiled by the phosphomimetic mutant NSF-Y83E. Molecular Human Reproduction 25, 344-358.
7) Quevedo MF, Bustos MA, Masone D, Bustos DM and Tomes CN (2019). GRAB recruitment by Rab27A-Rabphilin3a complex triggers Rab3A activation in human sperm exocytosis. Biochimica et Biophysica Acta – Molecular Cell Research. 1866, 612-622
8) Bustos MA, Lucchesi O, Ruete MC and Tomes CN (2018) Equal contribution. Membrane-permeable Rab27A is a regulator of the acrosome reaction: role of geranylgeranylation and guanine nucleotides. Cellular Signalling 44, 72-91. 9) Quevedo MF, Lucchesi O*, Bustos MA, Pocognoni CA, De la Iglesia PX and Tomes CN (2016). * Equal contribution. The Rab3A-22A Chimaera Prevents Sperm Exocytosis by Stabilizing Open Fusion Pores. The Journal of Biological Chemistry 291, 23101-23111.
10) Lucchesi O, Ruete MC, Bustos MA, QuevedoMF and Tomes CN (2016). The signaling module cAMP/Epac/Rap1/PLCε/IP3 mobilizes acrosomal calcium during sperm exocytosis. Biochimica et Biophysica Acta – Molecular Cell Research 1863, 544-561.
11) Tomes CN (2015). The proteins of exocytosis: lessons from the sperm model. The Biochemical Journal 465, 359-360.
12) Ruete MC, Lucchesi O, Bustos MA and Tomes CN (2014). Epac, Rap and secretory Rabs-driven signaling pathways act in concert during sperm exocytosis. Cell Communication and Signaling 12, 43.
13) Bustos MA, Roggero CM, de la Iglesia P, Mayorga LS and Tomes CN (2014). GTP-bound Rab3A exhibits consecutive positive and negative roles during human sperm dense core granule exocytosis. Journal of Molecular Cell Biology 6, 286-298.