Publicaciones
Hypercholesterolemia impaired sperm functionality in rabbits. Saez Lancellotti TE, Boarelli PV, Monclus MA, Cabrillana ME, Clementi MA, Espínola LS, Cid Barría JL, Vincenti AE, Santi AG, Fornés MW. PLoS One. 2010 Oct 18;5(10):e13457. doi: 10.1371/journal.pone.0013457.
Manchette-acrosome disorders during spermiogenesis and low efficiency of seminiferous tubules in hypercholesterolemic rabbit model. Simón L, Funes AK, Yapur MA, Cabrillana ME, Monclus MA, Boarelli PV, Vincenti AE, Saez Lancellotti TE, Fornés MW. PLoS One. 2017 Feb 27;12(2):e0172994. doi: 10.1371/journal.pone.0172994. eCollection 2017.
Semen quality and sperm function loss by hypercholesterolemic diet was recovered by addition of olive oil to diet in rabbit. Saez Lancellotti TE, Boarelli PV, Romero AA, Funes AK, Cid-Barria M, Cabrillana ME, Monclus MA, Simón L, Vicenti AE, Fornés MW. PLoS One. 2013;8(1):e52386. doi: 10.1371/journal.pone.0052386. Epub 2013 Jan 11.
Manchette-acrosome disorders and testicular efficiency decline observed in hypercholesterolemic rabbits are recovered with olive oil enriched diet. Simón L, Funes AK, Monclús MA, Colombo R, Cabrillana ME, Saez Lancellotti TE, Fornés MW. PLoS One. 2018 Aug 23;13(8):e0202748. doi: 10.1371/journal.pone.0202748. eCollection 2018.
Characterization of flagellar cysteine-rich sperm proteins involved in motility, by the combination of cellular fractionation, fluorescence detection, and mass spectrometry analysis. Cabrillana ME, Monclus MA, Sáez Lancellotti TE, Boarelli PV, Clementi MA, Vincenti AE, Yunes RF, Fornés MW. Cytoskeleton (Hoboken). 2011 Sep;68(9):491-500. doi: 10.1002/cm.20525. Epub 2011 Aug 16.
Thiols of flagellar proteins are essential for progressive motility in human spermatozoa. Cabrillana ME, Monclus MLÁ, Lancellotti TES, Boarelli PV, Vincenti AE, Fornés MM, Sanabria EA, Fornés MW. Reprod Fertil Dev. 2017 Jul;29(7):1435-1446. doi: 10.1071/RD16225.
Thiol oxidation by nitrosative stress: Cellular localization in human spermatozoa. Cabrillana ME, Uribe P, Villegas JV, Álvarez J, Sánchez R, Fornés MW. Syst Biol Reprod Med. 2016 Oct;62(5):325-34. doi: 10.1080/19396368.2016.1208782.
Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis. Uribe P, Cabrillana ME, Fornés MW, Treulen F, Boguen R, Isachenko V, Isachenko E, Sánchez R, Villegas JV. Asian J Androl. 2018 Nov-Dec;20(6):600-607. doi: 10.4103/aja.aja_29_18.
. Olive oil addition to the high-fat diet reduces methylglyoxal (MG-H1) levels increased in hypercholesterolemic rabbits. Simon, L., Lancellotti, T.E.S., Cortese, L., Barbieri, A., Fornes, M. 2019. Mediterranean Journal of Nutrition and Metabolism. 12(1), pp. 13-21
A chronic high-fat diet causes sperm head alterations in C57BL/6J mice. Funes A, Saez Lancellotti TE, Santillan LD, Della Vedova MC, Monclus MA, Cabrillana ME, Gomez Mejiba SE, Ramirez DC, Fornes MW. Heliyon. 2019 Nov 21;5(11):e02868. doi: 10.1016/j.heliyon.2019.e02868. eCollection 2019 Nov. PMID: 31844747 Free PMC article.
Impact of High Fat Diet on the Sterol Regulatory Element-Binding Protein 2 cholesterol pathway in the testicle. Abi K. Funes, Layla Simón, Regina Colombo, María Virginia Avena, María Monclus, Julieta Crescitelli, María E. Cabrillana, María Inés Conte, Niubys Cayado, Paola Boarelli, Miguel W. Fornés, Tania E. Saez Lancellotti. Mol Hum Reprod . 2021 May 8;27(5): gaab023. doi: 10.1093/molehr/gaab023.
Extra-virgin olive oil ameliorates high-fat diet-induced seminal and testicular disorders by modulating the cholesterol pathway. Funes AK, Avena MV, Ibañez J, Simón L, Ituarte L, Colombo R, Roldán A, Conte MI, Monclus MÁ, Boarelli P, Fornés MW, Saez Lancellotti TE. Andrology. 2023 Sep;11(6):1203-1217. doi: 10.1111/andr.13398. Epub 2023 Feb 11. PMID: 36695747