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Instituto de Histología y Embriología "Dr. Mario H. Burgos"


Publicaciones (Últimos años)

Aguilera, M. Berón, W. and Colombo, M.I.. Actin cytoskeleton participates in theearly events ofautophagosome formation upon starvation inducedautophagy” Autophagy 2012 Nov 1;8(11). [Epub ahead of print].

Fader, Claudio M., Aguilera, Milton and Colombo, María I.ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner” Autophagy 2012 Sep 5;8(12). [Epubaheadofprint). Este trabajo ha sido citado en FACULTY OF 1000.

Aguilera Milton Osmar, Berón W and Colombo María Isabel. “Actin cytoskeleton participates in the early event of autophagosome formation in starvet mediated autophagy”. Autophagy. 2012 Nov 1; 8 (11).

Fader Claudio, Aguilera MO y Colombo MI. “VAMP7-labeled amphisomes are transported to focal adhesions upon starvation-induced autophagy”. Autophagy. 2012 Dec;8(12):1741-56. doi: 10.4161/auto.21858.

Campoy, E. Mansilla, M.E. and Colombo, M.I. Endocytic SNAREs are involved in optimal Coxiella burnetii vacuole development”. Cell Microbiol. 2013 Jun;15(6):922-41.

Militello R.D., Munafó, D.B., Berón, W., López, L. A., Monier, S. Bruno Goud and Colombo, M.I."Rab24 is required for normal cell division”. Traffic.2013 May;14(5):502-18. doi: 10.1111/tra.12057. Epub 2013 Mar 8.

Delgui, L.R., Rodríguez, J.F. and Colombo, M.I. The endosomal pathway and the Golgi complex are involved in the Infectious Bursal Disease Virus life cycle. J Virol. 2013 Aug; 87(16):8993-9007.

Zarelli VE, Dawid IB. “The BTB-containing protein Kctd15 is SUMOylated in vivo”.  PLoS ONE 2013 8(9): e75016.

Zarelli VE, Dawid IB. “Inhibition of neural crest formation by Kctd15 involves regulation of Transcription factor AP-2”. Proc. Natl Acad Sci U S A. 2013 Feb 19; 110 (8): 2870-5.

Rovetta, A.I., Peña, D., Hernández Del Pino, R.E., Recalde, G., Pellegrini, J., Bigi, F., Musella, R.M., Palmero, D. J., Colombo, M.I.*, and  García, V.E.* IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis.Autophagy 2014 Dec 2;10(12):2109-21.* corresponding authors.

Fader Claudio*, Aguilera MO* y Colombo MI (*equal contribution). Autophagy response: manipulating the mTOR-controlled machinery by amino acids and pathogens”.  Amino Acids. 2014 Sep. DOI: 1-19.

Gimenez MC, Rodríguez Aguirre JF, Colombo MI*, Delgui LR*. Infectious bursal disease virus uptake involves macropinocytosis and trafficking to early endosomes in a Rab5-dependent manner.Cell  Microbiol. 2015 Jan 7. doi: 10.1111/cmi.12415. * corresponding authors.

Gimenez MC, Rodríguez Aguirre JF, Colombo MI*, Delgui LR*. Infectious bursal disease virus uptake involves macropinocytosis and trafficking to early endosomes in a Rab5-dependent manner.Cell  Microbiol. 2015 Jan 7. doi: 10.1111/cmi.12415. * corresponding authors.

Fader, C.M., Vergara A., Salassa, B., Moor, F. and Colombo, M.I. “Hemin induces mitophagy in a leukemic erythroblast cell line”. Biol Cell. 2016 Apr;108(4):77-95. doi: 10.1111/boc.201500058.

Amaya, C., Militello, R., Calligaris, S., and Colombo, M.I. "Rab24 interacts with the Rab7/RILP complex to regulate endosomal degradation", Traffic 2016 Aug 23. doi: 10.1111/tra.12431.

Dawid IB, Zarelli VE, Bogachek MV and Weigel RJ. Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. Reactome - a curated knowledgebase of biological pathways (2016).

Melani M, Valko A, Romero NM, Aguilera MO, Acevedo JM, Perez-Perri J, de la Riva-Carrasco RV, Katz MJ, Sorianello E, Juhász G,  Johansen T, Colombo MI and Wappner P. “Zonda is a novel early component of the autophagy pathway in Drosophila”. Mollecular Biology of the cell. 2017 Nov, 28(22):3070-3081. doi: 10.1091/mbc.E16-11-0767.

Mansilla Parejas, M.E., Bongiovanni, A., Lafont, F., and Colombo, M.I. Alterations of the Coxiella burnetii replicative vacuole membrane integrity and interplay with the autophagy pathway. Front Cell Infect Microbiol. 2017 Apr 24;7:112. doi: 10.3389/fcimb.2017.00112

María Milagros López de Armentia, María Celeste Gauron and María Isabel Colombo. Staphylococcus aureus alpha-toxin induces the formation of dynamic tubules labelled with LC3 within host cells in a Rab7 and Rab1b-dependent manner. Frontiers in Cell. and Infect. Microbiol 2017 Oct 4;7:431. doi: 10.3389/fcimb.2017.00431.

Gimenez MC, Zanetti FA, Terebiznik MR, Colombo MI, Delgui LR. Infectious Bursal Disease Virus hijacks endosomal membranes as the scaffolding structure for viral replication. J Virol. 2018 Mar 14. pii: JVI.01964-17. doi: 10.1128/JVI.01964-17.

Zarelli VE*, Giai C* and Colombo MI. (*, equally contribute). 2018 Chapter: Interaction of Mycobacterium tuberculosis with the host cells: a focus in the molecular mechanism involved in trafficking and autophagy. eBook: Tuberculosis, Science Medicine Group Open Access eBooks.

Dias, BRS, de Souza, CS, Almeida, NJ, Lima, JGB, Fukutani, KF, Dos Santos, TBS, França-Cost, J, Brodskyn, CI, de Menezes, JPB, Colombo, MI, Veras, PST1Autophagic induction greatly enhancesLeishmania major intracellular survival compared to Leishmania amazonensis in CBA/j-infected macrophages. Front Microbiol. 2018 Aug 15;9:1890. doi: 10.3389/fmicb.2018.01890. eCollection 2018. 

E. Silva, P. Villar, I. Niechi, C. Trigo, J.Muñoz, P. Pérez, F. Aguayo, V. Burzio, M. Varas-Godoy, A. Castro, E. Caamaño, M. Colombo and J. Tapia. CK2 inhibition with silmitasertib promotes methuosis-like cell death associated to catastrophic massive vacuolization of colorectal cancer cells". Cell Death and Disease. 2018 (in press). IF: 5.64.

María Eugenia Mansilla Pareja, Maria Celeste Gaurón, Esteban Robledo, Milton Aguilera, and María Isabel Colombo. The cAMP effectors, Rap2b and EPAC, are involved in the regulation of the development of the Coxiella burnetii-containing vacuole by altering the fusogenic capacity of the vacuole. PLOS ONE (in press)